Nosocomial infections in the pediatric intensive care units in Lithuania
- PMID: 19223703
Nosocomial infections in the pediatric intensive care units in Lithuania
Abstract
Objective: The aim of the study was to collect the data on incidence rates, pathogens of nosocomial infections, and antimicrobials for treatment of nosocomial infections.
Material and methods: Data were collected between March 2003 and December 2005 in five pediatric intensive care units using a modified patient-based HELICS protocol. Nosocomial infection was identified using the Centers for Disease Control definitions. All patients aged between 1 month and 18 years that stayed in the units for more than 48 hours were eligible for inclusion in this study.
Results: A total of 1239 patient admissions and 7601 patient-days were evaluated. In 169 children (13.6%), 186 nosocomial infections occurred. The incidence density was 24.5 per 1000 patient-days, the incidence rate--15.0 per 100 admissions. The highest incidence density was observed in the 6-12-year age group (31.2 per 1000 bed-days). Nosocomial infection rates per 1000 device-days were 28.8 for ventilator-associated pneumonia, 7.7--for bloodstream infection, and 3.4--for urinary tract infection. The most common site of infection was respiratory tract (58.8%). Secondary bacteremia developed in 18 (10.6%) patients. Haemophilus influenzae (20.1%), Acinetobacter spp. (14.2%), and Staphylococcus aureus (17.6%) were the most frequently isolated microorganisms. The most common antimicrobials used were first- and second-generation cephalosporins 74 (31.0%) and broad-spectrum penicillins 70 (29.3%).
Conclusions: In Lithuanian pediatric intensive care units, the incidence rates of nosocomial infections were comparable to the available data from other countries, except for the ventilator-associated pneumonia rate, which was relatively high. H. influenzae, Acinetobacter spp., and S. aureus were the most prevalent pathogens. The first- and second-generation cephalosporins and broad-spectrum penicillins were the most common antimicrobials in the treatment of nosocomial infections.
Similar articles
-
Nosocomial infections in pediatric intensive care units in the United States. National Nosocomial Infections Surveillance System.Pediatrics. 1999 Apr;103(4):e39. doi: 10.1542/peds.103.4.e39. Pediatrics. 1999. PMID: 10103331
-
Reduction of nosocomial infections and mortality attributable to nosocomial infections in pediatric intensive care units in Lithuania.Medicina (Kaunas). 2009;45(3):203-13. Medicina (Kaunas). 2009. PMID: 19357450
-
Trends in nosocomial infections and multidrug-resistant microorganisms in Spanish pediatric intensive care units.Enferm Infecc Microbiol Clin. 2016 May;34(5):286-92. doi: 10.1016/j.eimc.2015.07.010. Epub 2015 Sep 11. Enferm Infecc Microbiol Clin. 2016. PMID: 26364857
-
Nosocomial infections in a pediatric intensive care unit.Crit Care Med. 1988 Mar;16(3):233-7. doi: 10.1097/00003246-198803000-00005. Crit Care Med. 1988. PMID: 3277780 Review.
-
Nosocomial infections and multidrug-resistant bacterial organisms in the pediatric intensive care unit.Indian J Pediatr. 2011 Feb;78(2):176-84. doi: 10.1007/s12098-010-0253-4. Epub 2010 Oct 9. Indian J Pediatr. 2011. PMID: 20936380 Review.
Cited by
-
Study of plasmid mediated quinolone resistance genes among Escherichia coli and Klebsiella pneumoniae isolated from pediatric patients with sepsis.Sci Rep. 2024 May 24;14(1):11849. doi: 10.1038/s41598-024-61357-z. Sci Rep. 2024. PMID: 38783019 Free PMC article.
-
Antimicrobial Resistance and the Prevalence of the Panton-Valentine Leukocidin Gene among Clinical Isolates of Staphylococcus aureus in Lithuania.Pol J Microbiol. 2024 Mar 4;73(1):21-28. doi: 10.33073/pjm-2024-003. eCollection 2024 Mar 1. Pol J Microbiol. 2024. PMID: 38437463 Free PMC article.
-
Risk factors and cost of nosocomial infections in pediatric patients with traumatic brain injury.North Clin Istanb. 2023 Nov 20;10(6):761-768. doi: 10.14744/nci.2023.26037. eCollection 2023. North Clin Istanb. 2023. PMID: 38328718 Free PMC article.
-
Pattern and Frequency of Nosocomial Infections in the Pediatric Intensive Care Unit at East Jeddah General Hospital, Saudi Arabia.Cureus. 2023 Oct 24;15(10):e47561. doi: 10.7759/cureus.47561. eCollection 2023 Oct. Cureus. 2023. PMID: 38021580 Free PMC article.
-
Prevalence, Clinical Profile and Risk Factors of Nosocomial Infection in Ayder Pediatric Intensive Care Unit, Tigray, Ethiopia.Int J Gen Med. 2022 Sep 9;15:7145-7153. doi: 10.2147/IJGM.S384233. eCollection 2022. Int J Gen Med. 2022. PMID: 36110918 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous