Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Jun:26 Suppl 8:7-12.
doi: 10.1157/13126266.

[Clinical data I. Clinical experience with tenofovir in combination with nonnucleoside analogue transcriptase inhibitors]

[Article in Spanish]
J I Bernardino de la Serna  1 , M Mora Rillo, J R Arribas López
Affiliations
Review

[Clinical data I. Clinical experience with tenofovir in combination with nonnucleoside analogue transcriptase inhibitors]

[Article in Spanish]
J I Bernardino de la Serna et al. Enferm Infecc Microbiol Clin. 2008 Jun.

Abstract

Highly active antirretroviral therapy has transformed the prognosis of patient infected with human immunodeficiency virus. The efficacy of these drugs has shifted the clinicians; attention to other therapeutic aspects like QD regimens, fixed dose combinations and clinical safety. Tenofovir disoproxil fumarate(TDF) is a nucleoside monophosphate (nucleotide) analogue that inhibits reverse trascriptase enzyme. It's administered in a q.d. regimen and it's recommended by most of the clinical guidelines as a start regimen in combination with two other drugs. Currently more than 5 years of clinical experience is accumulated and confirmed that a combination of tenofovir and a nonnucleoside analogue transcriptase inhibitor is a comfortable, safe, highly effective and low pill burden regimen.

PubMed Disclaimer

Similar articles

See all similar articles

MeSH terms

LinkOut - more resources