doi: 10.1016/j.devcel.2008.12.011.
Chaos begets order: asynchronous cell contractions drive epithelial morphogenesis
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- PMID: 19154712
- DOI: 10.1016/j.devcel.2008.12.011
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Chaos begets order: asynchronous cell contractions drive epithelial morphogenesis
Dev Cell.
2009 Jan.
Free article
Abstract
Apical cell contraction triggers tissue folding and invagination in epithelia. During Drosophila gastrulation, ventral furrow formation was thought to be driven by smooth, purse-string-like constriction of an acto-myosin belt underlying adherens junctions. Now Martin et al. report in Nature that ventral furrow formation is triggered by asynchronous pulsed contractions of the apical acto-myosin cortex in individual cells.
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