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Review
. 2008 Jun;50(6):677-88.
doi: 10.1097/JOM.0b013e3181757a27.

Occupational electromagnetic fields and leukemia and brain cancer: an update to two meta-analyses

Leeka Kheifets  1 , Jason Monroe, Ximena Vergara, Gabor Mezei, Abdelmonem A Afifi
Affiliations
Review

Occupational electromagnetic fields and leukemia and brain cancer: an update to two meta-analyses

Leeka Kheifets et al. J Occup Environ Med. 2008 Jun.

Abstract

Objective: To update past meta-analyses on occupational electromagnetic fields (EMF) and adult brain cancer and leukemia.

Methods: We collected and evaluated all relevant 1993 to 2007 publications. Summary estimates were obtained using various weighting schemes. To explore sources of heterogeneity, study characteristics were examined using regression analysis.

Results: Overall, for new studies, both brain cancer and leukemia showed small increases in risk estimates, 10% and 13%, respectively. Notably, pooled risk estimates were lower than in past meta-analyses, and leukemia subtypes showed no consistent pattern when past and present meta-analyses were compared.

Conclusions: The lack of a clear pattern of EMF exposure and outcome risk does not support a hypothesis that these exposures are responsible for the observed excess risk. Findings were not sensitive to assumptions, influential studies, weighting schemes, publication bias, study characteristics, or funding source.

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