Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Jun;65(6):3259-67.
doi: 10.1128/JVI.65.6.3259-3267.1991.

The Q300 gene: a novel transcription unit induced in simian virus 40-infected and -transformed mouse cells

S Wagner  1 , G Cullmann, R Knippers
Affiliations

The Q300 gene: a novel transcription unit induced in simian virus 40-infected and -transformed mouse cells

S Wagner et al. J Virol. 1991 Jun.

Abstract

The Q300 element is a single-copy 233-bp genomic mouse DNA fragment carrying a high-affinity binding site for the simian virus 40 (SV40) large T antigen. This element was used to screen an EMBL3 mouse genomic library. We could identify a genomic clone containing an approximately 500-bp transcribed region flanking the Q300 element. The transcribed region, termed the Q300 transcription unit or Q300 gene, is overexpressed in acutely SV40-infected or SV40-transformed mouse and rat cells. The Q300 gene includes an open reading frame which has the coding potential for a small polypeptide with an extremely hydrophobic N terminus and a hydrophilic C terminus. The deduced polypeptide has some similarity with the papillomavirus E5 oncoprotein.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Oncogene. 1987 May;1(2):119-29 - PubMed
    1. Nucleic Acids Res. 1989 May 25;17(10):3899-908 - PubMed
    1. Mol Biol Med. 1987 Apr;4(2):63-80 - PubMed
    1. Cell. 1987 Sep 11;50(6):847-61 - PubMed
    1. Biochim Biophys Acta. 1987 Oct 9;910(1):1-10 - PubMed

Publication types

MeSH terms

LinkOut - more resources