Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Apr;18(2):105-14.
doi: 10.1016/j.semradonc.2007.10.007.

Using microarray analysis as a prognostic and predictive tool in oncology: focus on breast cancer and normal tissue toxicity

Dimitry S A Nuyten  1 , Marc J van de Vijver
Affiliations
Review

Using microarray analysis as a prognostic and predictive tool in oncology: focus on breast cancer and normal tissue toxicity

Dimitry S A Nuyten et al. Semin Radiat Oncol. 2008 Apr.

Abstract

Microarray analysis makes it possible to study the expression levels of tens of thousands of genes in one single experiment and is widely available for research purposes. Gene expression profiling is currently being used in many research projects aimed at identifying gene expression signatures in malignant tumors associated with prognosis and response to therapy. An important goal of such research is to develop gene expression-based diagnostic tests that can be used to guide therapy in cancer patients. Here we provide examples of studies using microarrays, especially focusing on breast cancer, in a wide range of fields including prediction of prognosis, distant metastasis and local recurrence, therapy response to radio- and chemotherapy, and normal tissue response.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

MeSH terms