Molecular typing and epidemiology of non-polio enteroviruses isolated from Yunnan Province, the People's Republic of China
- PMID: 18297723
- DOI: 10.1002/jmv.21122
Molecular typing and epidemiology of non-polio enteroviruses isolated from Yunnan Province, the People's Republic of China
Abstract
This report presents an overview of human enteroviruses in Yunnan Province, the People's Republic of China. A total of 210 non-polioviruses isolated under acute flaccid paralysis (AFP) surveillance during a total study period of 5 years--1997 to 2000 and 2004--were examined. Of the 210 non-poliovirus isolates, 12 adenoviruses were serologically identified, and the remaining 198 isolates were used for molecular typing. The viral genomes of 195 non-polio enteroviruses (NPEVs) on VP1 partial region of virus capsid were translated to the corresponding amino acid sequences; these were compared with those of prototype strains. Based on molecular typing, 5 isolates were classified into 5 serotypes of the human enterovirus A species, 158 isolates, into 35 serotypes of the human enterovirus B species; and 32 isolates, into 6 serotypes of the human enterovirus C species. Viruses belonging to the human enterovirus D species were not isolated. Thus, under AFP surveillance, the human enterovirus B species accounted for 75.2% of the 210 isolates, and it was considered the predominant species. This was followed by human enterovirus C (12.2%), adenovirus (5.7%), and human enterovirus A (2.4%). Further, molecular analysis suggested that several serotypes of human enteroviruses B and C that exhibited genetic polymorphism were indigenous. Molecular typing methods may aid in understanding the epidemiology of NPEVs in Yunnan Province.
Similar articles
-
[Study on the molecular typing and epidemiology of non-polio enteroviruses isolated from Yunnan province, China].Zhonghua Liu Xing Bing Xue Za Zhi. 2007 Apr;28(4):346-9. Zhonghua Liu Xing Bing Xue Za Zhi. 2007. PMID: 17850701 Chinese.
-
New enteroviruses, EV-93 and EV-94, associated with acute flaccid paralysis in the Democratic Republic of the Congo.J Med Virol. 2007 Apr;79(4):393-400. doi: 10.1002/jmv.20825. J Med Virol. 2007. PMID: 17311342
-
[Study on the molecular typing and epidemiology of non-polio enterovirus in Yunnan Province, China during 2006-2010].Bing Du Xue Bao. 2013 Mar;29(2):169-75. Bing Du Xue Bao. 2013. PMID: 23757848 Chinese.
-
Basic rationale, current methods and future directions for molecular typing of human enterovirus.Expert Rev Mol Diagn. 2007 Jul;7(4):419-34. doi: 10.1586/14737159.7.4.419. Expert Rev Mol Diagn. 2007. PMID: 17620049 Review.
-
Role of recombination in evolution of enteroviruses.Rev Med Virol. 2005 May-Jun;15(3):157-67. doi: 10.1002/rmv.457. Rev Med Virol. 2005. PMID: 15578739 Review.
Cited by
-
Molecular Characteristics of Enterovirus B83 Strain Isolated from a Patient with Acute Viral Myocarditis and Global Transmission Dynamics.Viruses. 2023 Jun 12;15(6):1360. doi: 10.3390/v15061360. Viruses. 2023. PMID: 37376658 Free PMC article.
-
Environmental Monitoring for Enteroviruses in Maputo, Mozambique-2018.Pathogens. 2022 Apr 29;11(5):527. doi: 10.3390/pathogens11050527. Pathogens. 2022. PMID: 35631048 Free PMC article.
-
Whole-genome analysis of coxsackievirus B3 reflects its genetic diversity in China and worldwide.Virol J. 2022 Apr 18;19(1):69. doi: 10.1186/s12985-022-01796-0. Virol J. 2022. PMID: 35436962 Free PMC article.
-
Molecular Characterization of Coxsackievirus A24v from Feces and Conjunctiva Reveals Epidemiological Links.Microorganisms. 2021 Mar 5;9(3):531. doi: 10.3390/microorganisms9030531. Microorganisms. 2021. PMID: 33807540 Free PMC article.
-
Molecular Epidemiological, Serological, and Pathogenic Analysis of EV-B75 Associated With Acute Flaccid Paralysis Cases in Tibet, China.Front Microbiol. 2021 Jan 13;11:632552. doi: 10.3389/fmicb.2020.632552. eCollection 2020. Front Microbiol. 2021. PMID: 33584598 Free PMC article.
Publication types
MeSH terms
Substances
Associated data
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
LinkOut - more resources
Full Text Sources