Comment
doi: 10.1016/j.molcel.2008.01.008.
Linking differential chromatin loops to transcriptional decisions
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- PMID: 18243110
- DOI: 10.1016/j.molcel.2008.01.008
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Comment
Linking differential chromatin loops to transcriptional decisions
Mol Cell.
.
Free article
Abstract
GATA-1 and GATA-2 control proliferation and differentiation of hematopoietic progenitor cells via transcriptional regulation. In this issue of Molecular Cell, Jing et al. (2008) demonstrate that GATA factor exchange on the Kit locus directs a transcriptional switch by reconfiguring chromatin loops.
Comment on
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Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus.Mol Cell. 2008 Feb 1;29(2):232-42. doi: 10.1016/j.molcel.2007.11.020. Mol Cell. 2008. PMID: 18243117 Free PMC article.
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