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Review
. 2007 Sep 7;130(5):784-95.
doi: 10.1016/j.cell.2007.08.031.

Imaging in systems biology

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Free article
Review

Imaging in systems biology

Sean G Megason et al. Cell. .
Free article

Abstract

Most systems biology approaches involve determining the structure of biological circuits using genomewide "-omic" analyses. Yet imaging offers the unique advantage of watching biological circuits function over time at single-cell resolution in the intact animal. Here, we discuss the power of integrating imaging tools with more conventional -omic approaches to analyze the biological circuits of microorganisms, plants, and animals.

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