Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants

doi:10.2174/157018006778194655

. 2006;3(8):586-592.

doi: 10.2174/157018006778194655.

Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants

Liljana Stevceva¹, Marcin Moniuszko, Maria Grazia Ferrari

Affiliations

PMID: 17496983
PMCID: PMC1868013
DOI: 10.2174/157018006778194655

Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants

Liljana Stevceva et al. Lett Drug Des Discov. 2006.

. 2006;3(8):586-592.

doi: 10.2174/157018006778194655.

Authors

Liljana Stevceva¹, Marcin Moniuszko, Maria Grazia Ferrari

Affiliation

¹ Partners AIDS Research Center, MGH, Harvard Medical School, CNY Build. 149, Room 5234e, Charlestown, MA 02129, USA.

PMID: 17496983
PMCID: PMC1868013
DOI: 10.2174/157018006778194655

Abstract

In this paper we review and discuss three of the most exciting and promising cytokines for therapeutic intervention and immunomodulation of immune responses including those on mucosal surfaces. The main properties of IL-12, IL-15 and IL-7 are described and the studies utilizing these cytokines as immunomodulators and vaccine adjuvants discussed.

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References

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1. Ahlers JD, Belyakov IM, Berzofsky JA. Curr Mol Med. 2003;3(3):285–301. - PubMed
1. Brandhuber BJ, Boone T, Kenney WC, McKay DB. Science. 1987;238(4834):1707–9. - PubMed
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[1] Stevceva L, Ferrari MG. Curr Pharm Des. 2005;11(6):801–11. - PubMed

[2] Stevceva L, Ferrari MG. Curr Pharm Des. 2005;11(6):801–11. - PubMed

[3] Ahlers JD, Belyakov IM, Berzofsky JA. Curr Mol Med. 2003;3(3):285–301. - PubMed

[4] Ahlers JD, Belyakov IM, Berzofsky JA. Curr Mol Med. 2003;3(3):285–301. - PubMed

[5] Brandhuber BJ, Boone T, Kenney WC, McKay DB. Science. 1987;238(4834):1707–9. - PubMed

[6] Brandhuber BJ, Boone T, Kenney WC, McKay DB. Science. 1987;238(4834):1707–9. - PubMed

[7] Ma X, Aste-Amezaga M, Trinchieri G. Ann NY Acad Sci. 1996;795:13–25. - PubMed

[8] Ma X, Aste-Amezaga M, Trinchieri G. Ann NY Acad Sci. 1996;795:13–25. - PubMed

[9] Chua AO, Wilkinson VL, Presky DH, Gubler U. J Immunol. 1995;155(9):4286–94. - PubMed

[10] Chua AO, Wilkinson VL, Presky DH, Gubler U. J Immunol. 1995;155(9):4286–94. - PubMed

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Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants

Affiliation

Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants

Authors

Affiliation

Abstract

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