doi: 10.1093/jnci/55.5.1243.
Attenuation of herpesvirus saimiri for marmosets after successive passage in cell culture at 39 degrees C
- PMID: 173864
- DOI: 10.1093/jnci/55.5.1243
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Attenuation of herpesvirus saimiri for marmosets after successive passage in cell culture at 39 degrees C
J Natl Cancer Inst.
1975 Nov.
Abstract
A variant of Herpesvirus saimiri (HVS) stably attenuated for marmosets was isolated after serial passage of wild-type HVS in cell culture at 39 degrees C. Marmosets previously inoculated with attenuated virus experienced a significant delay in the development of lymphoma when challenged with wild-type HVS.
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