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Review
. 2006 Nov;12(11):1638-43.
doi: 10.3201/eid1211.060152.

Emerging infections and pregnancy

Affiliations
Review

Emerging infections and pregnancy

Denise J Jamieson et al. Emerg Infect Dis. 2006 Nov.

Abstract

A key component of the response to emerging infections is consideration of special populations, including pregnant women. Successful pregnancy depends on adaptation of the woman's immune system to tolerate a genetically foreign fetus. Although the immune system changes are not well understood, a shift from cell-mediated immunity toward humoral immunity is believed to occur. These immunologic changes may alter susceptibility to and severity of infectious diseases in pregnant women. For example, pregnancy may increase susceptibility to toxoplasmosis and listeriosis and may increase severity of illness and increase mortality rates from influenza and varicella. Compared with information about more conventional disease threats, information about emerging infectious diseases is quite limited. Pregnant women's altered response to infectious diseases should be considered when planning a response to emerging infectious disease threats.

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Comment in

  • Pregnancy and emerging diseases.
    Anker M. Anker M. Emerg Infect Dis. 2007 Mar;13(3):518-9; author reply 519. doi: 10.3201/eid1303.061345. Emerg Infect Dis. 2007. PMID: 17552124 Free PMC article. No abstract available.

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References

    1. Centers for Disease Control and Prevention. Preventing emerging infectious diseases. A strategy for the 21st century overview of the updated CDC plan. MMWR Recomm Rep. 1998;47:1–14. - PubMed
    1. Gaunt G, Ramin K. Immunological tolerance of the human fetus. Am J Perinatol. 2001;18:299–312. 10.1055/s-2001-17861 - DOI - PubMed
    1. Szekeres-Bartho J. Immunological relationship between the mother and the fetus. Int Rev Immunol. 2002;21:471–95. 10.1080/08830180215017 - DOI - PubMed
    1. Elenkov IJ, Wilder RL, Bakalov VK, Link AA, Dimitrov MA, Fisher S, et al. IL-12, TNF-alpha, and hormonal changes during late pregnancy and early postpartum: implications for autoimmune disease activity during these times. J Clin Endocrinol Metab. 2001;86:4933–8. 10.1210/jc.86.10.4933 - DOI - PubMed
    1. Runmarker B, Andersen O. Pregnancy is associated with a lower risk of onset and a better prognosis in multiple sclerosis. Brain. 1995;118:253–61. 10.1093/brain/118.1.253 - DOI - PubMed

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