The polymerase in its labyrinth: mechanisms and implications of RNA recombination
- PMID: 1712518
- PMCID: PMC7134375
- DOI: 10.1016/0168-9525(91)90434-r
The polymerase in its labyrinth: mechanisms and implications of RNA recombination
Abstract
The wide variety of RNA viruses, and the diseases associated with them, may result in part from the capacity of RNA genomes to evolve through genetic recombination. Here we address the mechanism of RNA recombination, and ask questions about its prevalence and purpose in nature.
Similar articles
-
The puzzle of RNA recombination.FEBS Lett. 1999 Oct 22;460(1):1-5. doi: 10.1016/s0014-5793(99)01282-x. FEBS Lett. 1999. PMID: 10571050 Free PMC article. Review.
-
Evolution of RNA viruses.Ann N Y Acad Sci. 1980;354:492-7. doi: 10.1111/j.1749-6632.1980.tb27988.x. Ann N Y Acad Sci. 1980. PMID: 6939406
-
Reverse genetics of negative-strand RNA viruses: closing the circle.Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8804-6. doi: 10.1073/pnas.96.16.8804. Proc Natl Acad Sci U S A. 1999. PMID: 10430844 Free PMC article. Review. No abstract available.
-
New insights into the mechanisms of RNA recombination.Virology. 1997 Aug 18;235(1):1-9. doi: 10.1006/viro.1997.8681. Virology. 1997. PMID: 9300032 Review. No abstract available.
-
Proceedings: Improved synthetic templates for the RNA-instructed RNA polymerase of bacteriophage Q beta.Arch Int Physiol Biochim. 1974 Oct;82(4):773. Arch Int Physiol Biochim. 1974. PMID: 4141444 No abstract available.
Cited by
-
Nonhomologous RNA-RNA recombination events at the 3' nontranslated region of the Sindbis virus genome: hot spots and utilization of nonviral sequences.J Virol. 1996 Aug;70(8):5153-64. doi: 10.1128/JVI.70.8.5153-5164.1996. J Virol. 1996. PMID: 8764023 Free PMC article.
-
Genetic recombination of poliovirus in a cell-free system.Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13786-91. doi: 10.1073/pnas.94.25.13786. Proc Natl Acad Sci U S A. 1997. PMID: 9391105 Free PMC article.
-
Principles of molecular organization, expression, and evolution of closteroviruses: over the barriers.Adv Virus Res. 1996;47:119-58. doi: 10.1016/s0065-3527(08)60735-6. Adv Virus Res. 1996. PMID: 8895832 Free PMC article. Review.
-
Dissecting RNA recombination in vitro: role of RNA sequences and the viral replicase.EMBO J. 1998 Apr 15;17(8):2392-403. doi: 10.1093/emboj/17.8.2392. EMBO J. 1998. PMID: 9545250 Free PMC article.
-
Nonreplicative RNA recombination in poliovirus.J Virol. 1999 Nov;73(11):8958-65. doi: 10.1128/JVI.73.11.8958-8965.1999. J Virol. 1999. PMID: 10516001 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources