Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus

doi:10.1084/jem.173.2.423

Comparative Study

. 1991 Feb 1;173(2):423-7.

doi: 10.1084/jem.173.2.423.

Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus

J Arribas¹, M Luz Rodríguez, R Alvarez-Do Forno, J G Castaño

Affiliations

PMID: 1703207
PMCID: PMC2118784
DOI: 10.1084/jem.173.2.423

Comparative Study

Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus

J Arribas et al. J Exp Med. 1991.

. 1991 Feb 1;173(2):423-7.

doi: 10.1084/jem.173.2.423.

Authors

J Arribas¹, M Luz Rodríguez, R Alvarez-Do Forno, J G Castaño

Affiliation

¹ Departamento de Bioquímica, Facultad de Medicina de la UAM, Spain.

PMID: 1703207
PMCID: PMC2118784
DOI: 10.1084/jem.173.2.423

Abstract

Sera from patients with systemic lupus erythematosus contain specific autoantibodies directed against different polypeptide components of the multicatalytic proteinase (also known as proteasome or prosome). These human autoantibodies, in contrast to polyclonal antibodies obtained in rabbits against the purified enzyme, recognize highly conserved epitopes of the multicatalytic proteinase polypeptides from yeast to human.

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References

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[1] FEBS Lett. 1988 Dec 5;241(1-2):239-45 - PubMed

[2] FEBS Lett. 1988 Dec 5;241(1-2):239-45 - PubMed

[3] Nature. 1970 Aug 15;227(5259):680-5 - PubMed

[4] Nature. 1970 Aug 15;227(5259):680-5 - PubMed

[5] Biochem Biophys Res Commun. 1989 Nov 15;164(3):1253-61 - PubMed

[6] Biochem Biophys Res Commun. 1989 Nov 15;164(3):1253-61 - PubMed

[7] J Biol Chem. 1988 Nov 5;263(31):16209-17 - PubMed

[8] J Biol Chem. 1988 Nov 5;263(31):16209-17 - PubMed

[9] Biochem J. 1989 Jan 1;257(1):265-9 - PubMed

[10] Biochem J. 1989 Jan 1;257(1):265-9 - PubMed

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Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus

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Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus

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