Review
doi: 10.1038/nrn1954.
Epub 2006 Aug 2.
The origin and specification of cortical interneurons
Affiliations
- PMID: 16883309
- DOI: 10.1038/nrn1954
Item in Clipboard
Review
The origin and specification of cortical interneurons
Nat Rev Neurosci.
2006 Sep.
Abstract
GABA-containing interneurons are crucial to both the development and function of the cerebral cortex. Unlike cortical projection neurons, which have a relatively conserved set of characteristics, interneurons include multiple phenotypes that vary on morphological, physiological and neurochemical axes. This diversity, and the relatively late, context-dependent maturation of defining features, has challenged efforts to uncover the transcriptional control of cortical interneuron development. Here, we discuss recent data that are beginning to illuminate the origins and specification of distinct subgroups of cortical interneurons.
Similar articles
-
Secreted factors from ventral telencephalon induce the differentiation of GABAergic neurons in cortical cultures.Eur J Neurosci. 2006 Dec;24(11):2967-77. doi: 10.1111/j.1460-9568.2006.05194.x. Eur J Neurosci. 2006. PMID: 17156358
-
The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populations.Nat Neurosci. 2002 Dec;5(12):1279-87. doi: 10.1038/nn971. Nat Neurosci. 2002. PMID: 12411960
-
Sonic hedgehog maintains the identity of cortical interneuron progenitors in the ventral telencephalon.Development. 2005 Nov;132(22):4987-98. doi: 10.1242/dev.02090. Epub 2005 Oct 12. Development. 2005. PMID: 16221724
-
Control of tangential/non-radial migration of neurons in the developing cerebral cortex.Neurochem Int. 2007 Jul-Sep;51(2-4):121-31. doi: 10.1016/j.neuint.2007.05.006. Epub 2007 May 21. Neurochem Int. 2007. PMID: 17588709 Review.
-
[Origin of cortical interneurons: basic concepts and clinical implications].Rev Neurol. 2002 Oct 16-31;35(8):743-51. Rev Neurol. 2002. PMID: 12402228 Review. Spanish.
Cited by
-
From trans to cis: transcriptional regulatory networks in neocortical development.Trends Genet. 2015 Feb;31(2):77-87. doi: 10.1016/j.tig.2014.12.004. Epub 2015 Jan 24. Trends Genet. 2015. PMID: 25624274 Free PMC article. Review.
-
Paracrine Role for Somatostatin Interneurons in the Assembly of Perisomatic Inhibitory Synapses.J Neurosci. 2020 Sep 23;40(39):7421-7435. doi: 10.1523/JNEUROSCI.0613-20.2020. Epub 2020 Aug 26. J Neurosci. 2020. PMID: 32847968 Free PMC article.
-
Meningeal defects alter the tangential migration of cortical interneurons in Foxc1hith/hith mice.Neural Dev. 2012 Jan 17;7:2. doi: 10.1186/1749-8104-7-2. Neural Dev. 2012. PMID: 22248045 Free PMC article.
-
Tsc1 Loss in VIP-Lineage Cortical Interneurons Results in More VIP+ Interneurons and Enhanced Excitability.Cells. 2023 Dec 26;13(1):52. doi: 10.3390/cells13010052. Cells. 2023. PMID: 38201256 Free PMC article.
-
Exact distinction of excitatory and inhibitory neurons in neural networks: a study with GFP-GAD67 neurons optically and electrophysiologically recognized on multielectrode arrays.Front Neural Circuits. 2012 Sep 6;6:63. doi: 10.3389/fncir.2012.00063. eCollection 2012. Front Neural Circuits. 2012. PMID: 22973197 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
