Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 Jul;10(3):199-210.
doi: 10.1007/s10911-005-9581-9.

Intrauterine breast development and the mammary myoepithelial lineage

Francine Jolicoeur  1
Affiliations
Review

Intrauterine breast development and the mammary myoepithelial lineage

Francine Jolicoeur. J Mammary Gland Biol Neoplasia. 2005 Jul.

Abstract

As their name implies, the myoepithelial cells found at the epithelial-mesenchymal interface of the human mammary gland disclose features suggestive of a dual epithelial-like and muscle-like differentiation, i.e. they co-express various keratins and vimentin intermediate filaments, as well as smooth muscle-related antigens. This article provides an overview of the literature on intrauterine breast development with special emphasis on the myoepithelial component of the fetal human mammary gland epithelium. It discusses original and recently published immunohistochemical data on myoepithelial precursors and reasserts the relevance of developmental, morphological fetal tissue-based studies to the understanding and the clinical management of adult diseases.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Annu Rev Physiol. 1997;59:575-99 - PubMed
    1. Adv Anat Pathol. 1999 Jul;6(4):218-26 - PubMed
    1. Edinb Med J. 1934 Dec;41(12):653-682 - PubMed
    1. Lab Invest. 1985 Mar;52(3):243-56 - PubMed
    1. Am J Pathol. 2000 Dec;157(6):1769-75 - PubMed

Publication types

MeSH terms

LinkOut - more resources