A dedicated Wnt secretion factor
- PMID: 16678089
- DOI: 10.1016/j.cell.2006.04.018
A dedicated Wnt secretion factor
Abstract
The Wnt family of signaling proteins mediates cell-cell communication during development. In this issue of Cell, Bänziger et al. (2006) and Bartscherer et al. (2006) identify Wntless/Evi, a multipass transmembrane protein in the secretory pathway of Wnt-producing cells that promotes Wnt secretion.
Comment on
-
Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells.Cell. 2006 May 5;125(3):509-22. doi: 10.1016/j.cell.2006.02.049. Cell. 2006. PMID: 16678095
-
Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.Cell. 2006 May 5;125(3):523-33. doi: 10.1016/j.cell.2006.04.009. Cell. 2006. PMID: 16678096
Similar articles
-
Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells.Cell. 2006 May 5;125(3):509-22. doi: 10.1016/j.cell.2006.02.049. Cell. 2006. PMID: 16678095
-
Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.Cell. 2006 May 5;125(3):523-33. doi: 10.1016/j.cell.2006.04.009. Cell. 2006. PMID: 16678096
-
Lipid-independent secretion of a Drosophila Wnt protein.J Biol Chem. 2008 Jun 20;283(25):17092-8. doi: 10.1074/jbc.M802059200. Epub 2008 Apr 22. J Biol Chem. 2008. PMID: 18430724 Free PMC article.
-
Helping Wingless take flight: how WNT proteins are secreted.Nat Rev Mol Cell Biol. 2007 Apr;8(4):331-6. doi: 10.1038/nrm2141. Epub 2007 Mar 7. Nat Rev Mol Cell Biol. 2007. PMID: 17342185 Review.
-
The role of Evi/Wntless in exporting Wnt proteins.Development. 2023 Feb 15;150(3):dev201352. doi: 10.1242/dev.201352. Epub 2023 Feb 10. Development. 2023. PMID: 36763105 Free PMC article. Review.
Cited by
-
Wnt family members regulating osteogenesis and their origins.J Bone Miner Metab. 2024 Sep 16. doi: 10.1007/s00774-024-01554-y. Online ahead of print. J Bone Miner Metab. 2024. PMID: 39283365 Review.
-
Colonic healing requires Wnt produced by epithelium as well as Tagln+ and Acta2+ stromal cells.Development. 2022 Jan 1;149(1):dev199587. doi: 10.1242/dev.199587. Epub 2022 Jan 12. Development. 2022. PMID: 34910127 Free PMC article.
-
Osteoblast-Specific Wnt Secretion Is Required for Skeletal Homeostasis and Loading-Induced Bone Formation in Adult Mice.J Bone Miner Res. 2022 Jan;37(1):108-120. doi: 10.1002/jbmr.4445. Epub 2021 Oct 11. J Bone Miner Res. 2022. PMID: 34542191 Free PMC article.
-
Ghrelin octanoylation by ghrelin O-acyltransferase: protein acylation impacting metabolic and neuroendocrine signalling.Open Biol. 2021 Jul;11(7):210080. doi: 10.1098/rsob.210080. Epub 2021 Jul 28. Open Biol. 2021. PMID: 34315274 Free PMC article. Review.
-
TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) Interaction.Front Cell Dev Biol. 2020 Nov 26;8:599890. doi: 10.3389/fcell.2020.599890. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33324648 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases