Skip to main page content
U.S. flag

An official website of the United States government

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 Dec;33(Pt 6):1313-5.
doi: 10.1042/BST0331313.

Two functionally distinct pools of Src kinases for PDGF receptor signalling

Affiliations
Review

Two functionally distinct pools of Src kinases for PDGF receptor signalling

L Veracini et al. Biochem Soc Trans. 2005 Dec.

Abstract

The cytoplasmic tyrosine kinases of the Src family (SFK) play important roles in cell responses induced by growth factors, including cell growth, survival and migration. Here, we review how SFK participate in PDGF (platelet-derived growth factor) receptor signalling leading to DNA synthesis and actin assembly. Furthermore, evidence for a spatial compartmentalization of SFK signalling is also discussed.

PubMed Disclaimer

Similar articles

Cited by

Publication types

MeSH terms

LinkOut - more resources