Bats are natural reservoirs of SARS-like coronaviruses
- PMID: 16195424
- DOI: 10.1126/science.1118391
Bats are natural reservoirs of SARS-like coronaviruses
Abstract
Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.
Comment in
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Virology. What links bats to emerging infectious diseases?Science. 2005 Oct 28;310(5748):628-9. doi: 10.1126/science.1120872. Science. 2005. PMID: 16254175 No abstract available.
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Voucher specimens for SARS-linked bats.Science. 2006 Feb 24;311(5764):1099-100; author reply 1099-100. doi: 10.1126/science.311.5764.1099. Science. 2006. PMID: 16497914 No abstract available.
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