Variance imputation for overviews of clinical trials with continuous response
- PMID: 1619456
- DOI: 10.1016/0895-4356(92)90054-q
Variance imputation for overviews of clinical trials with continuous response
Abstract
Overviews of clinical trials are an efficient and important means of summarizing information about a particular scientific area. When the outcome is a continuous variable, both treatment effect and variance estimates are required to construct a confidence interval for the overall treatment effect. Often, only partial information about the variance is provided in the publication of the clinical trial. This paper provides heuristic suggestions for variance imputation based on partial variance information. Both pretest-posttest (parallel groups) and crossover designs are considered. A key idea is to use separate sources of incomplete information to help choose a better variance estimate. The imputation suggestions are illustrated with a data set.
Similar articles
-
Estimation issues in clinical trials and overviews.Stat Med. 1990 Jun;9(6):657-71. doi: 10.1002/sim.4780090612. Stat Med. 1990. PMID: 2145623
-
Imputing variance estimates do not alter the conclusions of a meta-analysis with continuous outcomes: a case study of changes in renal function after living kidney donation.J Clin Epidemiol. 2007 Mar;60(3):228-40. doi: 10.1016/j.jclinepi.2006.06.018. Epub 2006 Oct 23. J Clin Epidemiol. 2007. PMID: 17292016 Review.
-
Four-fold table cell frequencies imputation in meta analysis.Stat Med. 2006 Jul 15;25(13):2299-322. doi: 10.1002/sim.2287. Stat Med. 2006. PMID: 16025540
-
The impact of stopping rules on heterogeneity of results in overviews of clinical trials.Biometrics. 1992 Mar;48(1):41-53. Biometrics. 1992. PMID: 1581492
-
Understanding research synthesis (meta-analysis).Annu Rev Public Health. 1996;17:1-23. doi: 10.1146/annurev.pu.17.050196.000245. Annu Rev Public Health. 1996. PMID: 8724213 Review.
Cited by
-
Interventions for replacing missing teeth: different times for loading dental implants.Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD003878. doi: 10.1002/14651858.CD003878.pub5. Cochrane Database Syst Rev. 2013. PMID: 23543525 Free PMC article. Review.
-
Therapeutic intervention for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): a systematic review and meta-analysis.PLoS One. 2012;7(8):e41941. doi: 10.1371/journal.pone.0041941. Epub 2012 Aug 1. PLoS One. 2012. PMID: 22870266 Free PMC article. Review.
-
Smoking cessation for improving mental health.Cochrane Database Syst Rev. 2021 Mar 9;3(3):CD013522. doi: 10.1002/14651858.CD013522.pub2. Cochrane Database Syst Rev. 2021. PMID: 33687070 Free PMC article.
-
Effects of inspiratory muscle training on lung function parameter in swimmers: a systematic review and meta-analysis.Front Sports Act Living. 2024 Sep 16;6:1429902. doi: 10.3389/fspor.2024.1429902. eCollection 2024. Front Sports Act Living. 2024. PMID: 39351143 Free PMC article.
-
Asynchronous and synchronous teleconsultation for diabetes care: a systematic literature review.J Diabetes Sci Technol. 2010 May 1;4(3):666-84. doi: 10.1177/193229681000400323. J Diabetes Sci Technol. 2010. PMID: 20513335 Free PMC article. Review.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
