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Review
. 2005;25(4):251-62.
doi: 10.1615/critrevimmunol.v25.i4.10.

Mechanisms regulating lymphocytic infiltration of the thyroid in murine models of thyroiditis

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Review

Mechanisms regulating lymphocytic infiltration of the thyroid in murine models of thyroiditis

Sergio A Lira et al. Crit Rev Immunol. 2005.

Abstract

The autoimmune diseases of the thyroid are the most prevalent autoimmune diseases in man. In these diseases, the thyroid is invariably infiltrated by lymphocytes, which play a major role in pathogenesis. In this review, we discuss the mechanisms associated with lymphocytic infiltration of the thyroid, examining different models of thyroid autoimmune disease in mice.

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