Evaluation of a new Plasmodium lactate dehydrogenase assay (OptiMAL-IT) for the detection of malaria
- PMID: 16117960
- DOI: 10.1016/s0035-9203(03)80100-1
Evaluation of a new Plasmodium lactate dehydrogenase assay (OptiMAL-IT) for the detection of malaria
Abstract
The new OptiMAL-IT(R) rapid diagnostic test for malaria was evaluated in 271 patients in Thailand with uncomplicated malaria between June and July 2002. The sensitivity and specificity for the diagnosis of Plasmodium falciparum parasites were 88% and 92%, respectively. For species other than P. falciparum, the sensitivity was 65% and specificity was 99%. The performance of the new test decreased markedly at low levels of parasitaemia.
Similar articles
-
Assessment of three new parasite lactate dehydrogenase (pan-pLDH) tests for diagnosis of uncomplicated malaria.Trans R Soc Trop Med Hyg. 2008 Jan;102(1):25-31. doi: 10.1016/j.trstmh.2007.09.014. Epub 2007 Nov 26. Trans R Soc Trop Med Hyg. 2008. PMID: 18031779
-
Field evaluation of rapid diagnostic tests for malaria in Yaounde, Cameroon.Acta Trop. 2013 Feb;125(2):214-9. doi: 10.1016/j.actatropica.2012.10.002. Epub 2012 Oct 17. Acta Trop. 2013. PMID: 23085326
-
A comparison of two rapid field immunochromatographic tests to expert microscopy in the diagnosis of malaria.Acta Trop. 2002 Apr;82(1):51-9. doi: 10.1016/s0001-706x(02)00031-1. Acta Trop. 2002. PMID: 11904103
-
Laboratory diagnosis of malaria: conventional and rapid diagnostic methods.Arch Pathol Lab Med. 2013 Jun;137(6):805-11. doi: 10.5858/arpa.2011-0602-RA. Arch Pathol Lab Med. 2013. PMID: 23721276 Review.
-
Rapid diagnostic tests for malaria parasites.Clin Microbiol Rev. 2002 Jan;15(1):66-78. doi: 10.1128/CMR.15.1.66-78.2002. Clin Microbiol Rev. 2002. PMID: 11781267 Free PMC article. Review.
Cited by
-
Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries.Cochrane Database Syst Rev. 2011 Jul 6;2011(7):CD008122. doi: 10.1002/14651858.CD008122.pub2. Cochrane Database Syst Rev. 2011. PMID: 21735422 Free PMC article. Review.
-
Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria.Malar J. 2009 Oct 27;8:241. doi: 10.1186/1475-2875-8-241. Malar J. 2009. PMID: 19860920 Free PMC article.
-
Comparative Study on the Effects of Chloroquine and Artesunate on Histopathological Damages Caused by Plasmodium berghei in Four Vital Organs of Infected Albino Mice.Malar Res Treat. 2012;2012:960758. doi: 10.1155/2012/960758. Epub 2012 Jun 24. Malar Res Treat. 2012. PMID: 22792509 Free PMC article.
-
Deployment of early diagnosis and mefloquine-artesunate treatment of falciparum malaria in Thailand: the Tak Malaria Initiative.PLoS Med. 2006 Jun;3(6):e183. doi: 10.1371/journal.pmed.0030183. PLoS Med. 2006. PMID: 16719547 Free PMC article.
-
Development of insulated isothermal PCR for rapid on-site malaria detection.Malar J. 2016 Mar 1;15:134. doi: 10.1186/s12936-016-1183-z. Malar J. 2016. PMID: 26931146 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical