doi: 10.1086/432576.
Epub 2005 Jul 19.
Eflornithine is safer than melarsoprol for the treatment of second-stage Trypanosoma brucei gambiense human African trypanosomiasis
Affiliations
- PMID: 16080099
- DOI: 10.1086/432576
Item in Clipboard
Eflornithine is safer than melarsoprol for the treatment of second-stage Trypanosoma brucei gambiense human African trypanosomiasis
Clin Infect Dis.
.
Abstract
Patients with second-stage human African trypanosomiasis treated with eflornithine (n = 251) in 2003 in Kiri, southern Sudan, had an adjusted relative risk of death of 0.2 and experienced significantly fewer cutaneous and neurological adverse effects than did patients who were treated with melarsoprol in 2001 and 2002 (n = 708).
Similar articles
-
Melarsoprol-free drug combinations for second-stage Gambian sleeping sickness: the way to go.Clin Infect Dis. 2007 Dec 1;45(11):1443-5. doi: 10.1086/522983. Epub 2007 Oct 22. Clin Infect Dis. 2007. PMID: 17990226 No abstract available.
-
[A trial treatment with eflornithine of trypanosomiasis caused by Trypanosoma brucei gambiense in the Peoples Republic of the Congo].Med Trop (Mars). 1989 Apr-Jun;49(2):149-54. Med Trop (Mars). 1989. PMID: 2507863 Clinical Trial. French.
-
Production of sleeping-sickness treatment.Lancet. 1999 Sep 11;354(9182):955-6. doi: 10.1016/S0140-6736(05)75709-3. Lancet. 1999. PMID: 10489988 No abstract available.
-
The treatment of human African trypanosomiasis.Adv Parasitol. 1994;33:1-47. doi: 10.1016/s0065-308x(08)60410-8. Adv Parasitol. 1994. PMID: 8122565 Review. No abstract available.
-
Eflornithine for the treatment of human African trypanosomiasis.Parasitol Res. 2003 Jun;90 Supp 1:S49-52. doi: 10.1007/s00436-002-0766-5. Epub 2002 Dec 10. Parasitol Res. 2003. PMID: 12811548 Review.
Cited by
-
The History of the ABC Proteins in Human Trypanosomiasis Pathogens.Pathogens. 2022 Aug 30;11(9):988. doi: 10.3390/pathogens11090988. Pathogens. 2022. PMID: 36145420 Free PMC article. Review.
-
New Series of Imidazoles Showed Promising Growth Inhibitory and Curative Potential Against Trypanosoma Infection.Yale J Biol Med. 2021 Jun 30;94(2):199-207. eCollection 2021 Jun. Yale J Biol Med. 2021. PMID: 34211341 Free PMC article.
-
Easy-To-Access Quinolone Derivatives Exhibiting Antibacterial and Anti-Parasitic Activities.Molecules. 2021 Feb 20;26(4):1141. doi: 10.3390/molecules26041141. Molecules. 2021. PMID: 33672753 Free PMC article.
-
Safety and efficacy of hydroxyurea and eflornithine against most blood parasites Babesia and Theileria.PLoS One. 2020 Feb 13;15(2):e0228996. doi: 10.1371/journal.pone.0228996. eCollection 2020. PLoS One. 2020. PMID: 32053698 Free PMC article.
-
Centering Patient Expectations of a Novel Home-Based Oral Drug Treatment among T. b. rhodesiense Human African Trypanosomiasis Patients in Uganda.Trop Med Infect Dis. 2020 Jan 21;5(1):16. doi: 10.3390/tropicalmed5010016. Trop Med Infect Dis. 2020. PMID: 31973101 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
