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. 2005 Jul 1;33(Web Server issue):W447-50.
doi: 10.1093/nar/gki378.

CONREAL web server: identification and visualization of conserved transcription factor binding sites

Eugene Berezikov  1 , Victor Guryev, Edwin Cuppen
Affiliations

CONREAL web server: identification and visualization of conserved transcription factor binding sites

Eugene Berezikov et al. Nucleic Acids Res. .

Abstract

The use of orthologous sequences and phylogenetic footprinting approaches have become popular for the recognition of conserved and potentially functional sequences. Several algorithms have been developed for the identification of conserved transcription factor binding sites (TFBSs), which are characterized by their relatively short and degenerative recognition sequences. The CONREAL (conserved regulatory elements anchored alignment) web server provides a versatile interface to CONREAL-, LAGAN-, BLASTZ- and AVID-based predictions of conserved TFBSs in orthologous promoters. Comparative analysis using different algorithms can be started by keyword without any prior sequence retrieval. The interface is available at http://conreal.niob.knaw.nl.

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Figures

Figure 1
Figure 1
Input: CONREAL orthologous sequence retrieval and submission page view. See text for details.
Figure 2
Figure 2
Output: representation of predicted conserved TFBS. See text for details.
See this image and copyright information in PMC

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References

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