BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks
- PMID: 15972284
- DOI: 10.1093/bioinformatics/bti551
BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks
Abstract
The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to determine which Gene Ontology (GO) terms are significantly overrepresented in a set of genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant functional themes of the tested gene set on the GO hierarchy, and takes advantage of Cytoscape's versatile visualization environment to produce an intuitive and customizable visual representation of the results.
Similar articles
-
GenePro: a Cytoscape plug-in for advanced visualization and analysis of interaction networks.Bioinformatics. 2006 Sep 1;22(17):2178-9. doi: 10.1093/bioinformatics/btl356. Bioinformatics. 2006. PMID: 16921162
-
Complex networks approach to gene expression driven phenotype imaging.Bioinformatics. 2005 Oct 15;21(20):3846-51. doi: 10.1093/bioinformatics/bti625. Epub 2005 Aug 16. Bioinformatics. 2005. PMID: 16105902
-
NetAtlas: a Cytoscape plugin to examine signaling networks based on tissue gene expression.In Silico Biol. 2008;8(1):47-52. In Silico Biol. 2008. PMID: 18430989
-
Stochastic P systems and the simulation of biochemical processes with dynamic compartments.Biosystems. 2008 Mar;91(3):458-72. doi: 10.1016/j.biosystems.2006.12.009. Epub 2007 Jul 17. Biosystems. 2008. PMID: 17728055 Review.
-
Tools for visually exploring biological networks.Bioinformatics. 2007 Oct 15;23(20):2651-9. doi: 10.1093/bioinformatics/btm401. Epub 2007 Aug 25. Bioinformatics. 2007. PMID: 17720984 Review.
Cited by
-
High hydrostatic pressure activates transcription factors involved in Saccharomyces cerevisiae stress tolerance.Curr Pharm Biotechnol. 2012 Dec;13(15):2712-20. doi: 10.2174/138920112804724891. Curr Pharm Biotechnol. 2012. PMID: 23072392 Free PMC article.
-
The gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition.Breast Cancer Res. 2012 Jul 27;14(4):R113. doi: 10.1186/bcr3236. Breast Cancer Res. 2012. PMID: 22839103 Free PMC article.
-
MIGGRI: A multi-instance graph neural network model for inferring gene regulatory networks for Drosophila from spatial expression images.PLoS Comput Biol. 2023 Nov 8;19(11):e1011623. doi: 10.1371/journal.pcbi.1011623. eCollection 2023 Nov. PLoS Comput Biol. 2023. PMID: 37939200 Free PMC article.
-
Transcriptome response signatures associated with the overexpression of a mitochondrial uncoupling protein (AtUCP1) in tobacco.PLoS One. 2015 Jun 24;10(6):e0130744. doi: 10.1371/journal.pone.0130744. eCollection 2015. PLoS One. 2015. PMID: 26106890 Free PMC article.
-
Gene expression and metabolism preceding soft scald, a chilling injury of 'Honeycrisp' apple fruit.BMC Genomics. 2016 Oct 12;17(1):798. doi: 10.1186/s12864-016-3019-1. BMC Genomics. 2016. PMID: 27733113 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases