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Review
. 2005 Aug;21(8):421-4.
doi: 10.1016/j.tig.2005.06.004.

Hox clusters as models for vertebrate genome evolution

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Review

Hox clusters as models for vertebrate genome evolution

Simone Hoegg et al. Trends Genet. 2005 Aug.

Abstract

The surprising variation in the number of Hox clusters and the genomic architecture within vertebrate lineages, especially within the ray-finned fish, reflects a history of duplications and subsequent lineage-specific gene loss. Recent research on the evolution of conserved non-coding sequences (CNS) in Hox clusters promises to reveal interesting results for functional and phenotypic diversification.

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