Hox clusters as models for vertebrate genome evolution
- PMID: 15967537
- DOI: 10.1016/j.tig.2005.06.004
Hox clusters as models for vertebrate genome evolution
Abstract
The surprising variation in the number of Hox clusters and the genomic architecture within vertebrate lineages, especially within the ray-finned fish, reflects a history of duplications and subsequent lineage-specific gene loss. Recent research on the evolution of conserved non-coding sequences (CNS) in Hox clusters promises to reveal interesting results for functional and phenotypic diversification.
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