ARDS in SARS: cytokine mediators and treatment implications

doi:10.1016/j.cyto.2004.09.002

. 2005 Jan 21;29(2):92-4.

doi: 10.1016/j.cyto.2004.09.002.

ARDS in SARS: cytokine mediators and treatment implications

Manuel Salto-Tellez, Emily Tan, Bing Lim

PMID: 15598444
PMCID: PMC7128468
DOI: 10.1016/j.cyto.2004.09.002

ARDS in SARS: cytokine mediators and treatment implications

Manuel Salto-Tellez et al. Cytokine. 2005.

. 2005 Jan 21;29(2):92-4.

doi: 10.1016/j.cyto.2004.09.002.

Authors

Manuel Salto-Tellez, Emily Tan, Bing Lim

PMID: 15598444
PMCID: PMC7128468
DOI: 10.1016/j.cyto.2004.09.002

No abstract available

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Figures

**Fig. 1**
Hypothetical model for the inflammatory cytokine basis of SARS/ARDS. Cascade of activation of key inflammatory mediators after lung parenchymal injury leading to ARDS is shown. The site of activity of several therapeutic agents is indicated. (MAPK, mitogen activated protein kinase; NF-κB, nuclear factor kappa B).

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References

1. Ksiazek T.G., Erdman D., Goldsmith C.S., Zaki S.R., Peret T., Emery S. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med. 2003;348:1953–1966. - PubMed
1. Peiris J.S., Lai S.T., Poon L.L., Guan Y., Yam L.Y., Lim W. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet. 2003;361:1319–1325. - PMC - PubMed
1. Donnelly S.C., Haslett C., Reid P.T., Grant I.S., Wallace W.A., Metz C.N. Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome. Nat Med. 1997;3:320–323. - PubMed
1. Ng P.C., Lam C.W., Li A.M., Wong C.K., Cheng F.W., Leung T.F. Inflammatory cytokine profile in children with severe acute respiratory syndrome. Pediatrics. 2004;113(1 Pt 1):e7–e14. - PubMed
1. Li Z., Guo X., Hao W., Wu Y., Ji Y., Zhao Y. The relationship between serum interleukins and T-lymphocyte subsets in patients with severe acute respiratory syndrome. Chin Med J (Engl) 2003;116(7):981–984. - PubMed

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[1] Ksiazek T.G., Erdman D., Goldsmith C.S., Zaki S.R., Peret T., Emery S. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med. 2003;348:1953–1966. - PubMed

[2] Ksiazek T.G., Erdman D., Goldsmith C.S., Zaki S.R., Peret T., Emery S. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med. 2003;348:1953–1966. - PubMed

[3] Peiris J.S., Lai S.T., Poon L.L., Guan Y., Yam L.Y., Lim W. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet. 2003;361:1319–1325. - PMC - PubMed

[4] Peiris J.S., Lai S.T., Poon L.L., Guan Y., Yam L.Y., Lim W. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet. 2003;361:1319–1325. - PMC - PubMed

[5] Donnelly S.C., Haslett C., Reid P.T., Grant I.S., Wallace W.A., Metz C.N. Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome. Nat Med. 1997;3:320–323. - PubMed

[6] Donnelly S.C., Haslett C., Reid P.T., Grant I.S., Wallace W.A., Metz C.N. Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome. Nat Med. 1997;3:320–323. - PubMed

[7] Ng P.C., Lam C.W., Li A.M., Wong C.K., Cheng F.W., Leung T.F. Inflammatory cytokine profile in children with severe acute respiratory syndrome. Pediatrics. 2004;113(1 Pt 1):e7–e14. - PubMed

[8] Ng P.C., Lam C.W., Li A.M., Wong C.K., Cheng F.W., Leung T.F. Inflammatory cytokine profile in children with severe acute respiratory syndrome. Pediatrics. 2004;113(1 Pt 1):e7–e14. - PubMed

[9] Li Z., Guo X., Hao W., Wu Y., Ji Y., Zhao Y. The relationship between serum interleukins and T-lymphocyte subsets in patients with severe acute respiratory syndrome. Chin Med J (Engl) 2003;116(7):981–984. - PubMed

[10] Li Z., Guo X., Hao W., Wu Y., Ji Y., Zhao Y. The relationship between serum interleukins and T-lymphocyte subsets in patients with severe acute respiratory syndrome. Chin Med J (Engl) 2003;116(7):981–984. - PubMed

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ARDS in SARS: cytokine mediators and treatment implications

ARDS in SARS: cytokine mediators and treatment implications

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