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Clinical Trial
. 2004 Sep-Oct:(5):62-7.

[Total immunization of children against influenza decreases morbidity in a number of diseases among elderly persons during influenza epidemic]

[Article in Russian]
Iu Z Gendon, A N Kaira, G A El'shina, R R Akhmadulina
  • PMID: 15554316
Clinical Trial

[Total immunization of children against influenza decreases morbidity in a number of diseases among elderly persons during influenza epidemic]

[Article in Russian]
Iu Z Gendon et al. Zh Mikrobiol Epidemiol Immunobiol. 2004 Sep-Oct.

Abstract

Immunization of children aged 3-6 years in kindergartens and school children aged 7-17 years against influenza with inactivated influenza vaccine was carried out in two districts of the Moscow region. The comparison of morbidity in influenza-like diseases among the immunized children with that among nonimmunized children in control districts revealed that the effectiveness of immunization was 60.9% in kindergartens and 68.8% in schools. The analysis of morbidity in a number of diseases among 158,451 elderly persons not immunized against influenza demonstrated that, in comparison with the control districts, in those districts where mass immunization of children was carried out morbidity in influenza-like diseases among elderly persons was 3.4 times lower and, out of other 10 diseases under study, morbidity in 8 diseases was 1.5-2.6 times lower. As indicated by the data obtained in this study, total anti-influenza immunization of children in organized groups not only essentially decreased influenza morbidity among children, but also greatly decreased morbidity in influenza and a number of diseases, appearing as complications of influenza infection, among nonimmunized elderly persons during influenza epidemic.

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