Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Nov;11(6):1002-7.
doi: 10.1128/CDLI.11.6.1002-1007.2004.

Impact of immune plasticity on development of cellular memory responses to human immunodeficiency virus type 1

Michael A Kolber  1
Affiliations

Impact of immune plasticity on development of cellular memory responses to human immunodeficiency virus type 1

Michael A Kolber. Clin Diagn Lab Immunol. 2004 Nov.
No abstract available

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
CD8+ T-cell differentiation pathway. The differentiation of CD8+ T cells is displayed as a linear model with various points where phenotypes can move between differentiation stages (double-headed arrows), as described in the text. A single-headed arrow represents a unidirectional differentiation step. The cells of most individuals with HIV disease have the phenotype displayed and can move to a later or earlier phenotype under the conditions shown. The cellular effector potential is shown to be increasing as the differentiation phenotype moves toward a fully differentiated chronic infection phenotype.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

  • Naive B Cell Output in HIV-Infected and HIV-Uninfected Children.
    Payne H, Chain G, Adams S, Hunter P, Luckhurst N, Gilmour K, Lewis J, Babiker A, Cotton M, Violari A, Gibb D, Callard R, Klein N. Payne H, et al. AIDS Res Hum Retroviruses. 2019 Jan;35(1):33-39. doi: 10.1089/AID.2018.0170. Epub 2018 Dec 26. AIDS Res Hum Retroviruses. 2019. PMID: 30298747 Free PMC article.

References

    1. Akbar, A. N., L. Terry, A. Timms, P. C. Beverley, and G. Janossy. 1988. Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J. Immunol. 140:2171-2178. - PubMed
    1. Al-Harthi, L., J. Siegel, J. Spritzler, J. Pottage, M. Agnoli, and A. Landay. 2000. Maximum suppression of HIV replication leads to the restoration of HIV-specific responses in early HIV disease. AIDS 14:761-770. - PubMed
    1. Altfeld, M., E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. 2001. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med. 193:169-180. - PMC - PubMed
    1. Altfeld, M., J. van Lunzen, N. Frahm, X. G. Yu, C. Schneider, R. L. Eldridge, M. E. Feeney, D. Meyer-Olson, H. J. Stellbrink, and B. D. Walker. 2002. Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection. J. Clin. Investig. 109:837-843. - PMC - PubMed
    1. Angel, J. B., K. G. Parato, A. Kumar, S. Kravcik, A. D. Badley, C. Fex, D. Ashby, E. Sun, and D. W. Cameron. 2001. Progressive human immunodeficiency virus-specific immune recovery with prolonged viral suppression. J. Infect. Dis. 183:546-554. - PubMed

MeSH terms