Review
doi: 10.1002/bies.950140204.
The rel family of proteins
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- PMID: 1533515
- DOI: 10.1002/bies.950140204
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Review
The rel family of proteins
Bioessays.
1992 Feb.
Abstract
The rel family of proteins can be defined as a group of proteins that share sequence homology over a 300 amino acid region termed the rel domain. The rel family comprises important regulatory proteins from a wide variety of species and includes the Drosophila morphogen dorsal, the mammalian transcription factor NF-kappa B, the avian oncogene v-rel, and the cellular proto-oncogene c-rel. Over the last two years it has become apparent that these proteins function as DNA-binding transcription factors, and that their activity is regulated at the level of subcellular localization.
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