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Clinical Trial
. 2004 Apr;70(4):189-91.

Hemofiltration in the prevention of radiocontrast agent induced nephropathy

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  • PMID: 15173694
Free article
Clinical Trial

Hemofiltration in the prevention of radiocontrast agent induced nephropathy

G Marenzi et al. Minerva Anestesiol. 2004 Apr.
Free article

Abstract

Aim: The aim of the study was to investigate the role of hemofiltration in preventing contrast nephropathy in patients with renal failure.

Methods: We randomized 114 renal failure patients undergoing percutaneous coronary interventions (PCI) to either peri-procedural hemofiltration or saline hydration.

Results: Contrast nephropathy occurred in 5% of hemofiltration-treated patients and in 50% in controls (P<0.01). In-hospital event rate as well as in-hospital and 1-year mortality rates were lower in patients treated with hemofiltration.

Conclusion: In patients with renal failure undergoing PCI, peri-procedural hemofiltration is effective for the prevention of contrast nephropathy, and is associated with improved in-hospital and long-term outcome.

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