Review
doi: 10.1038/nsmb779.
The mRNA cap-binding protein eIF4E in post-transcriptional gene expression
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- PMID: 15164008
- DOI: 10.1038/nsmb779
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Review
The mRNA cap-binding protein eIF4E in post-transcriptional gene expression
Nat Struct Mol Biol.
2004 Jun.
Free article
Abstract
Eukaryotic initiation factor 4E (eIF4E) has central roles in the control of several aspects of post-transcriptional gene expression and thereby affects developmental processes. It is also implicated in human diseases. This review explores the relationship between structural, biochemical and biophysical aspects of eIF4E and its function in vivo, including both long-established roles in translation and newly emerging ones in nuclear export and mRNA decay pathways.
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