Temporal subtraction of thorax CR images using a statistical deformation model
- PMID: 14606682
- DOI: 10.1109/TMI.2003.819291
Temporal subtraction of thorax CR images using a statistical deformation model
Abstract
We propose a voxel-based nonrigid registration algorithm for temporal subtraction of two-dimensional thorax X-ray computed radiography images of the same subject. The deformation field is represented by a B-spline with a limited number of degrees of freedom, that allows global rib alignment to minimize subtraction artifacts within the lung field without obliterating interval changes of clinically relevant soft-tissue abnormalities. The spline parameters are constrained by a statistical deformation model that is learned from a training set of manually aligned image pairs using principal component analysis. Optimization proceeds along the transformation components rather then along the individual spline coefficients, using pattern intensity of the subtraction image within the automatically segmented lung field region as the criterion to be minimized and applying a simulated annealing strategy for global optimization in the presence of multiple local optima. The impact of different transformation models with varying number of deformation modes is evaluated on a training set of 26 images using a leave-one-out strategy and compared to the manual registration result in terms of criterion value and deformation error. Registration quality is assessed on a second set of validation images by a human expert rating each subtraction image on screen. In 85% of the cases, the registration is subjectively rated to be adequate for clinical use.
Similar articles
-
Non-rigid image registration using a statistical spline deformation model.Inf Process Med Imaging. 2003 Jul;18:463-74. doi: 10.1007/978-3-540-45087-0_39. Inf Process Med Imaging. 2003. PMID: 15344480 Clinical Trial.
-
Temporal subtraction in chest radiography: automated assessment of registration accuracy.Med Phys. 2006 May;33(5):1239-49. doi: 10.1118/1.2184441. Med Phys. 2006. PMID: 16752558
-
A rigidity penalty term for nonrigid registration.Med Phys. 2007 Nov;34(11):4098-108. doi: 10.1118/1.2776236. Med Phys. 2007. PMID: 18072476
-
Deformable image registration of liver with consideration of lung sliding motion.Med Phys. 2011 Oct;38(10):5351-61. doi: 10.1118/1.3633902. Med Phys. 2011. PMID: 21992354
-
PET-CT image registration in the chest using free-form deformations.IEEE Trans Med Imaging. 2003 Jan;22(1):120-8. doi: 10.1109/TMI.2003.809072. IEEE Trans Med Imaging. 2003. PMID: 12703765
Cited by
-
Deformable image registration for temporal subtraction of chest radiographs.Int J Comput Assist Radiol Surg. 2014 Jul;9(4):513-22. doi: 10.1007/s11548-013-0947-y. Int J Comput Assist Radiol Surg. 2014. PMID: 24078349
-
Deformable medical image registration: a survey.IEEE Trans Med Imaging. 2013 Jul;32(7):1153-90. doi: 10.1109/TMI.2013.2265603. Epub 2013 May 31. IEEE Trans Med Imaging. 2013. PMID: 23739795 Free PMC article. Review.
-
Learning intervention-induced deformations for non-rigid MR-CT registration and electrode localization in epilepsy patients.Neuroimage Clin. 2015 Dec 10;10:291-301. doi: 10.1016/j.nicl.2015.12.001. eCollection 2016. Neuroimage Clin. 2015. PMID: 26900569 Free PMC article.
-
Low-Dimensional Non-Rigid Image Registration Using Statistical Deformation Models From Semi-Supervised Training Data.IEEE Trans Med Imaging. 2015 Jul;34(7):1522-1532. doi: 10.1109/TMI.2015.2404572. Epub 2015 Feb 16. IEEE Trans Med Imaging. 2015. PMID: 25720017 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
