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. 2003 Nov;9(11):S90-4.
doi: 10.1053/jlts.2003.50247.

Treatment of patients with hepatitis C virus on the waiting list

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Free article

Treatment of patients with hepatitis C virus on the waiting list

Gregory T Everson. Liver Transpl. 2003 Nov.
Free article

Abstract

1. Over 90% of patients with hepatitis C on the waiting list might be candidates for therapy with interferon plus ribavirin. 2. One must exercise caution in the treatment of these patients. Those with Child-Turcotte-Pugh score >11 or Model for End-Stage Liver Disease score >25 should be excluded from treatment. 3. Sustained virologic response (hepatitis C virus RNA-negative) is mainly dependent on viral genotype, with 50% of genotype 2 and 3 patients achieving sustained virologic response. 4. The ability to achieve sustained virologic response in genotype 1 patients is dependent on dose and duration of treatment. 5. Patients rendered hepatitis C virus RNA-negative pretransplantation may not experience posttransplantation recurrence.

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