Skip to main page content
U.S. flag

An official website of the United States government

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2003 Oct 30;96(3):289-95.
doi: 10.1016/j.vetmic.2003.07.005.

Disseminated pythiosis in three horses

Affiliations
Case Reports

Disseminated pythiosis in three horses

Janildo Ludolf Reis Jr et al. Vet Microbiol. .

Abstract

Three cases of equine subcutaneous pythiosis with dissemination to the internal organs were investigated. The subcutaneous lesions were observed on the mammary gland, nostrils and limbs of the infected horses. Histopathological analysis of the infected tissues revealed a strong eosinophilic reaction, with macrophages, mast cells and giant cells. Sparsely septated hyphal filaments of 4-6 microm diameter were identified in the center of the eosinophilic areas. Specific fluorescent antibody against Pythium insidiosum confirmed the hyphae in the infected tissues in three examined horses. In one of the three cases, the DNA sequences amplified from the infected subcutaneous tissues and internal organs, revealed that P. insidiosum's 18S SSU rDNA amplicons shared 100% identity with those sequences deposit in GenBank. This is the first report confirming by immunochemical and genetic techniques that P. insidiosum can disseminated from superficial to deep structures.

PubMed Disclaimer

Similar articles

  • Equine pythiosis: report in crossed bred (Criole Venezuelan) horses.
    Salas Y, Márquez A, Canelón J, Perazzo Y, Colmenárez V, López JA. Salas Y, et al. Mycopathologia. 2012 Dec;174(5-6):511-7. doi: 10.1007/s11046-012-9562-7. Epub 2012 Jul 7. Mycopathologia. 2012. PMID: 22772508
  • Equine pythiosis in Costa Rica: report of 39 cases.
    Mendoza L, Alfaro AA. Mendoza L, et al. Mycopathologia. 1986 May;94(2):123-9. doi: 10.1007/BF00437377. Mycopathologia. 1986. PMID: 3088454
  • Cutaneous pythiosis in horses from Brazil.
    Meireles MC, Riet-Correa F, Fischman O, Zambrano AF, Zambrano MS, Ribeiro GA. Meireles MC, et al. Mycoses. 1993 Mar-Apr;36(3-4):139-42. doi: 10.1111/j.1439-0507.1993.tb00702.x. Mycoses. 1993. PMID: 8366878
  • Cutaneous pythiosis in the horse.
    Chaffin MK, Schumacher J, McMullan WC. Chaffin MK, et al. Vet Clin North Am Equine Pract. 1995 Apr;11(1):91-103. doi: 10.1016/s0749-0739(17)30334-6. Vet Clin North Am Equine Pract. 1995. PMID: 7634168 Review.
  • Pythium insidiosum: an overview.
    Gaastra W, Lipman LJ, De Cock AW, Exel TK, Pegge RB, Scheurwater J, Vilela R, Mendoza L. Gaastra W, et al. Vet Microbiol. 2010 Nov 20;146(1-2):1-16. doi: 10.1016/j.vetmic.2010.07.019. Epub 2010 Jul 24. Vet Microbiol. 2010. PMID: 20800978 Review.

Cited by

Publication types

MeSH terms

LinkOut - more resources