Review
doi: 10.1016/0968-0004(92)90262-8.
The varieties of ribonuclease P
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- PMID: 1375791
- DOI: 10.1016/0968-0004(92)90262-8
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Review
The varieties of ribonuclease P
Trends Biochem Sci.
1992 May.
Abstract
Ribonuclease P is a ribozyme involved in tRNA processing that is present in all cells and organelles that synthesize tRNA. Most of our understanding of ribonuclease P derives from studies of the bacterial enzyme. This enzyme has been characterized biochemically and a secondary structure for the RNA subunit has been proposed. Isolation and characterization of ribonuclease P from diverse Archaea and Eukarya are now modifying and adding to our model of this unusual enzyme. The latter instances of RNase P differ from the bacterial version, but similarities are emerging.
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