Tracking evolution's footprints in the genome
- PMID: 12818003
- PMCID: PMC193687
- DOI: 10.1186/1475-4924-2-9
Tracking evolution's footprints in the genome
Abstract
The strategy of using 'phylogenetic footprinting' to find regulatory sites that are conserved between pairs of related complex genomes has led to the development of a suite of computational tools that succeed in finding functionally important transcription-factor-binding sequences.
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