GPCRDB information system for G protein-coupled receptors
- PMID: 12520006
- PMCID: PMC165550
- DOI: 10.1093/nar/gkg103
GPCRDB information system for G protein-coupled receptors
Abstract
The GPCRDB is a molecular class-specific information system that collects, combines, validates and disseminates heterogeneous data on G protein-coupled receptors (GPCRs). The database stores data on sequences, ligand binding constants and mutations. The system also provides computationally derived data such as sequence alignments, homology models, and a series of query and visualization tools. The GPCRDB is updated automatically once every 4-5 months and is freely accessible at http://www.gpcr.org/7tm/.
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References
-
- Gudermann T., Nurnberg,B. and Schultz,G. (1995) Receptors and G proteins as primary components of transmembrane signal transduction. Part 1. G-protein-coupled receptors: structure and function. J. Mol. Med., 73, 51–63. - PubMed
-
- Watson S. and Arkinstall,S. (eds) (1994) The G Protein Linked Receptor Facts Book. Academic Press, London, UK.
-
- Rana B.K. and Insel,P.A. (2002) G-protein-coupled receptor websites. Trends Pharmacol. Sci., 23, 535–536. - PubMed
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