Review
doi: 10.1016/s0960-9822(02)01352-0.
RNA interference: the fragile X syndrome connection
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- PMID: 12498706
- DOI: 10.1016/s0960-9822(02)01352-0
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Review
RNA interference: the fragile X syndrome connection
Curr Biol.
.
Free article
Abstract
Fragile X syndrome is caused by loss of expression of FMRP, a protein proposed to act as a regulator of mRNA translation which promotes synaptic maturation and function. Now FMRP has been found to associate with the RNP complex that mediates post-transcriptional silencing by RNAi.
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