doi: 10.1126/science.1076996.
Epub 2002 Sep 26.
Microfluidic large-scale integration
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- PMID: 12351675
- DOI: 10.1126/science.1076996
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Microfluidic large-scale integration
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Abstract
We developed high-density microfluidic chips that contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These fluidic devices are analogous to electronic integrated circuits fabricated using large-scale integration. A key component of these networks is the fluidic multiplexor, which is a combinatorial array of binary valve patterns that exponentially increases the processing power of a network by allowing complex fluid manipulations with a minimal number of inputs. We used these integrated microfluidic networks to construct the microfluidic analog of a comparator array and a microfluidic memory storage device whose behavior resembles random-access memory.
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