Review
doi: 10.1016/s1097-2765(02)00443-4.
CtBP, an unconventional transcriptional corepressor in development and oncogenesis
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- PMID: 11864595
- DOI: 10.1016/s1097-2765(02)00443-4
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Review
CtBP, an unconventional transcriptional corepressor in development and oncogenesis
Mol Cell.
2002 Feb.
Free article
Abstract
CtBP family proteins are conserved among vertebrates and invertebrates and function as transcriptional corepressors. They repress transcription in a histone deacetylase-dependent or -independent manner. CtBPs play important roles during development and oncogenesis. In this review, their unusual properties, the mechanisms of transcriptional repression, regulation, and their biological functions are discussed.
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