Review
doi: 10.1016/s0959-437x(01)00263-5.
Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes
Affiliations
- PMID: 11790554
- DOI: 10.1016/s0959-437x(01)00263-5
Item in Clipboard
Review
Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes
Curr Opin Genet Dev.
2002 Feb.
Abstract
Progression of resting quiescent G(0) cells into early G(1) and transition across the restriction point are highly regulated processes. Mutation of proto-oncogenes and tumor suppressor genes regulating these transitions are targeted during oncogenesis. Recent work has underscored the importance of the G(0) to early G(1) transition and metabolism to neoplastic cells.
Similar articles
-
Cancer cell cycles.Science. 1996 Dec 6;274(5293):1672-7. doi: 10.1126/science.274.5293.1672. Science. 1996. PMID: 8939849 Review.
-
Aberrations of the G1- and G1/S-regulating genes in human cancer.Prog Cell Cycle Res. 1997;3:211-20. doi: 10.1007/978-1-4615-5371-7_16. Prog Cell Cycle Res. 1997. PMID: 9552416 Review.
-
Cyclins and CDKS in development and cancer: lessons from genetically modified mice.Front Biosci. 2006 Jan 1;11:1164-88. doi: 10.2741/1871. Front Biosci. 2006. PMID: 16146805 Review.
-
The regulation of tumor suppressor genes by oncogenes.Methods Mol Biol. 2003;222:269-92. doi: 10.1385/1-59259-328-3:269. Methods Mol Biol. 2003. PMID: 12710693 No abstract available.
-
Molecular aspects of the mammalian cell cycle and cancer.Oncologist. 2002;7(1):73-81. doi: 10.1634/theoncologist.7-1-73. Oncologist. 2002. PMID: 11854549
Cited by
-
CycleTrak: a novel system for the semi-automated analysis of cell cycle dynamics.Dev Biol. 2012 May 1;365(1):189-95. doi: 10.1016/j.ydbio.2012.02.026. Epub 2012 Feb 25. Dev Biol. 2012. PMID: 22387844 Free PMC article.
-
Mip/LIN-9 can inhibit cell proliferation independent of the pocket proteins.Blood Cells Mol Dis. 2007 Nov-Dec;39(3):272-7. doi: 10.1016/j.bcmd.2007.05.006. Epub 2007 Jul 6. Blood Cells Mol Dis. 2007. PMID: 17618148 Free PMC article.
-
Potential four‑miRNA signature associated with T stage and prognosis of patients with pancreatic ductal adenocarcinoma identified by co‑expression analysis.Mol Med Rep. 2019 Jan;19(1):441-451. doi: 10.3892/mmr.2018.9663. Epub 2018 Nov 19. Mol Med Rep. 2019. PMID: 30483731 Free PMC article.
-
Small molecule regulators of Rb-E2F pathway as modulators of transcription.Biochim Biophys Acta. 2010 Oct-Dec;1799(10-12):788-94. doi: 10.1016/j.bbagrm.2010.07.004. Epub 2010 Jul 15. Biochim Biophys Acta. 2010. PMID: 20637913 Free PMC article. Review.
-
FRMD4A: A potential therapeutic target for the treatment of tongue squamous cell carcinoma.Int J Mol Med. 2016 Nov;38(5):1443-1449. doi: 10.3892/ijmm.2016.2745. Epub 2016 Sep 21. Int J Mol Med. 2016. PMID: 27666346 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
