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Review
. 2001 Dec;20(4):217-25.
doi: 10.1053/sder.2001.29379.

Pathophysiologic mechanisms in atopic dermatitis

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Review

Pathophysiologic mechanisms in atopic dermatitis

M Boguniewicz et al. Semin Cutan Med Surg. 2001 Dec.

Abstract

Atopic dermatitis is a common, chronic inflammatory skin disease that frequently predates the development of asthma and/or allergic rhinoconjunctivitis. Recent studies have provided new insights into how the complex interrelationship of genetic, environmental, and immunologic factors may contribute to the development of atopic dermatitis. This article examines some of the factors involved in chronic cutaneous inflammation in this disease. Greater understanding of the mechanisms that underlie the pathophysiology of atopic dermatitis may lead to improved treatment strategies for this increasingly common skin disease.

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