Performance appraisal of rapid on-site malaria diagnosis (ICT malaria Pf/Pv test) in relation to human resources at village level in Myanmar
- PMID: 11755428
- DOI: 10.1016/s0001-706x(01)00189-9
Performance appraisal of rapid on-site malaria diagnosis (ICT malaria Pf/Pv test) in relation to human resources at village level in Myanmar
Abstract
Logistic, economic and technical factors limit rapid access to microscopic confirmation of symptomatic diagnosis of malaria in many rural areas in endemic countries such as Myanmar. A study was conducted to evaluate a rapid on-site immunochromatographic test (ICT Malaria Pf/Pv) for detection of Plasmodium falciparum and P. vivax in two villages in the Taikkyi region of Myanmar. The ICT Malaria tests were performed by a volunteer health worker (VHW) in Yae-Aye-San village and by a professionally trained midwife (MW) in Kankone village. A total of 1000 symptomatic patients participated in the study by providing blood samples for an ICT test and for microscopy. The ICT performance indices, relative to microscopy, were better for the trained MW compared with the less experienced VHW. For P. falciparum and/or P. vivax infections, the sensitivities were 82.7% for the VHW compared with 93.7% for the MW. For P. falciparum infections, the sensitivities were 82.2% for the VHW and 91.3% for the MW, while the corresponding values for P. vivax infections were 66.7 and 79%, respectively. Although the test kit appeared to perform better in more experienced hands, this study questions whether this difference is related to the use of the ICT Malaria Pf/Pv test kit, or related to other factors such as differences in the quality of blood slides prepared by the VHW and MW for microscopic examination. Overall, the results suggest that a rapid diagnostic assay such as the ICT Malaria Pf/Pv test kit can be used in rural settings by relatively inexperienced persons, such as VHWs, with a reasonable degree of sensitivity, thus providing on-site confirmation of symptomatic diagnosis of malaria.
Similar articles
-
Field evaluation of the ICT Malaria Pf/Pv immunochromatographic test for the detection of asymptomatic malaria in a Plasmodium falciparum/vivax endemic area in Thailand.Am J Trop Med Hyg. 2002 Apr;66(4):379-83. doi: 10.4269/ajtmh.2002.66.379. Am J Trop Med Hyg. 2002. PMID: 12164291
-
Comparison of two commercial assays with expert microscopy for confirmation of symptomatically diagnosed malaria.J Clin Microbiol. 2002 Dec;40(12):4675-8. doi: 10.1128/JCM.40.12.4675-4678.2002. J Clin Microbiol. 2002. PMID: 12454171 Free PMC article.
-
Malarigen malaria Pf/Pv antigen rapid test: a simple and effective tool for diagnosis of malaria in the far-flung hilly areas of Bangladesh.Mymensingh Med J. 2010 Jan;19(1):94-9. Mymensingh Med J. 2010. PMID: 20046179 Clinical Trial.
-
Rapid immunochromatography-based detection of mixed-species malaria infection in Pakistan.Southeast Asian J Trop Med Public Health. 2005 May;36(3):562-4. Southeast Asian J Trop Med Public Health. 2005. PMID: 16124417
-
Evaluation of the performance of CareStart Malaria Pf/Pv Combo and Paracheck Pf tests for the diagnosis of malaria in Wondo Genet, southern Ethiopia.Acta Trop. 2009 Sep;111(3):321-4. doi: 10.1016/j.actatropica.2009.05.014. Epub 2009 May 29. Acta Trop. 2009. PMID: 19482001
Cited by
-
Accuracy of an Immunochromatographic Diagnostic Test (ICT Malaria Combo Cassette Test) Compared to Microscopy among under Five-Year-Old Children when Diagnosing Malaria in Equatorial Guinea.Malar Res Treat. 2010;2010:858427. doi: 10.4061/2010/858427. Epub 2010 Aug 4. Malar Res Treat. 2010. PMID: 22332024 Free PMC article.
-
Towards eliminating malaria in high endemic countries: the roles of community health workers and related cadres and their challenges in integrated community case management for malaria: a systematic review.Malar J. 2017 Jan 3;16(1):10. doi: 10.1186/s12936-016-1667-x. Malar J. 2017. PMID: 28049486 Free PMC article. Review.
-
Evaluation of the malaria rapid diagnostic test VIKIA malaria Ag Pf/Pan™ in endemic and non-endemic settings.Malar J. 2013 Jun 6;12:188. doi: 10.1186/1475-2875-12-188. Malar J. 2013. PMID: 23742633 Free PMC article.
-
Effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in Myanmar.Malar J. 2012 Sep 4;11:309. doi: 10.1186/1475-2875-11-309. Malar J. 2012. PMID: 22946985 Free PMC article. Clinical Trial.
-
Factors associated with utilization of community health workers in improving access to malaria treatment among children in Kenya.Malar J. 2012 Jul 30;11:248. doi: 10.1186/1475-2875-11-248. Malar J. 2012. PMID: 22846194 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical