Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2002 Jan 1;30(1):264-7.
doi: 10.1093/nar/30.1.264.

SCOP database in 2002: refinements accommodate structural genomics

Loredana Lo Conte  1 , Steven E Brenner, Tim J P Hubbard, Cyrus Chothia, Alexey G Murzin
Affiliations

SCOP database in 2002: refinements accommodate structural genomics

Loredana Lo Conte et al. Nucleic Acids Res. .

Abstract

The SCOP (Structural Classification of Proteins) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationships. Protein domains in SCOP are grouped into species and hierarchically classified into families, superfamilies, folds and classes. Recently, we introduced a new set of features with the aim of standardizing access to the database, and providing a solid basis to manage the increasing number of experimental structures expected from structural genomics projects. These features include: a new set of identifiers, which uniquely identify each entry in the hierarchy; a compact representation of protein domain classification; a new set of parseable files, which fully describe all domains in SCOP and the hierarchy itself. These new features are reflected in the ASTRAL compendium. The SCOP search engine has also been updated, and a set of links to external resources added at the level of domain entries. SCOP can be accessed at http://scop.mrc-lmb.cam.ac.uk/scop.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Murzin A., Brenner,S.E., Hubbard,T.J.P. and Chothia,C. (1995) SCOP: a Structural Classification of Proteins database for the investigation of sequences and structures. J. Mol. Biol., 247, 536–540. - PubMed
    1. Brenner S.E., Chothia,C., Hubbard,T.J.P. and Murzin,A. (1996) Understanding protein structure: using SCOP for fold interpretation. Methods Enzymol., 266, 635–643. - PubMed
    1. Bernstein F.C., Koetzle,T.F., Williams,G.J.B., Meyer,E.F., Brice,M.D., Rodgers,J.R., Kennard,O., Shimanouchi,T. and Tasumi,M. (1977) The Protein Data Bank: a computer-based archival file for macromolecular structures. J. Mol. Biol., 112, 535–542. - PubMed
    1. Westbrook J., Feng,Z., Jain,S., Bhat,T.N., Thanki,N., Ravichandran,V., Gilliland,G.L., Bluhm,W., Weissig,H., Greer,D.S., Bourne,P.E. and Berman,H.M. (2002) The Protein Data Bank: unifying the archive. Nucleic Acids Res., 30, 245–248. - PMC - PubMed
    1. Chandonia J.-M., Walker,N.S., Lo Conte,L., Koehl,P., Levitt,M. and Brenner,S.E. (2002) ASTRAL compendium enhancements. Nucleic Acids Res., 30, 260–263. - PMC - PubMed