Review
doi: 10.1053/srin.2001.25622.
Extended-spectrum beta-lactamases
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- PMID: 11562896
- DOI: 10.1053/srin.2001.25622
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Review
Extended-spectrum beta-lactamases
Semin Respir Infect.
2001 Sep.
Abstract
Extended-spectrum beta lactamase (ESBL) producing gram-negative bacilli are a growing concern, especially because the species of organisms producing these enzymes are increasing. Bacteria possessing these enzymes are resistant to third-generation cephalosporins--antimicrobial agents important for inpatient therapy. These resistant organisms are clinically important because they result in increased morbidity and mortality. Additionally, some laboratories may have difficulty detecting ESBL-producing organisms. These and other issues are discussed in this article.
Copyright 2001 by W.B. Saunders Company
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