Formation of Peyer's patches
- PMID: 11532399
- DOI: 10.1016/s0959-437x(00)00233-1
Formation of Peyer's patches
Abstract
Formation of Peyer's patches requires complex interactions between the gut epithelium, the mesenchyme, and bone-marrow-derived hematopoietic progenitors. The first Peyer's patches anlage appear around embryonic day 15.5, when the endoderm has undergone transition to a simple epithelium, the lymphatic vessels have reached the intestinal mucosa, and mesenchymal cells have started to form clusters. Recent data using knockout mice provide insight into the molecular nature of the signals that mediate Peyer's patch ontogeny. These include members of the tumor-necrosis factor family and homeostatic chemokines.
Similar articles
-
Peyer's patch M cells derived from Lgr5(+) stem cells require SpiB and are induced by RankL in cultured "miniguts".Mol Cell Biol. 2012 Sep;32(18):3639-47. doi: 10.1128/MCB.00434-12. Epub 2012 Jul 9. Mol Cell Biol. 2012. PMID: 22778137 Free PMC article.
-
Lectin histochemistry reveals the appearance of M-cells in Peyer's patches of SCID mice after syngeneic normal bone marrow transplantation.J Histochem Cytochem. 1998 Feb;46(2):143-8. doi: 10.1177/002215549804600202. J Histochem Cytochem. 1998. PMID: 9446820
-
Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis.J Exp Med. 2001 Mar 5;193(5):621-30. doi: 10.1084/jem.193.5.621. J Exp Med. 2001. PMID: 11238592 Free PMC article.
-
Particle uptake by Peyer's patches: a pathway for drug and vaccine delivery.Expert Opin Drug Deliv. 2004 Nov;1(1):141-63. doi: 10.1517/17425247.1.1.141. Expert Opin Drug Deliv. 2004. PMID: 16296726 Review.
-
M cells in Peyer's patches of the intestine.Int Rev Cytol. 1996;167:91-159. doi: 10.1016/s0074-7696(08)61346-7. Int Rev Cytol. 1996. PMID: 8768493 Review.
Cited by
-
Pyloric tonsil as a novel gut-associated lymphoepithelial organ of the chicken.J Anat. 2007 Sep;211(3):407-11. doi: 10.1111/j.1469-7580.2007.00766.x. Epub 2007 Jun 25. J Anat. 2007. PMID: 17593219 Free PMC article.
-
Cataloguing the postnatal small intestinal transcriptome during the first postnatal month.bioRxiv [Preprint]. 2024 Dec 27:2024.09.25.612672. doi: 10.1101/2024.09.25.612672. bioRxiv. 2024. PMID: 39386454 Free PMC article. Preprint.
-
Enteroviruses: A Gut-Wrenching Game of Entry, Detection, and Evasion.Viruses. 2019 May 21;11(5):460. doi: 10.3390/v11050460. Viruses. 2019. PMID: 31117206 Free PMC article. Review.
-
Blocking the alpha 4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site.J Clin Invest. 2006 Mar;116(3):715-23. doi: 10.1172/JCI26091. Epub 2006 Feb 9. J Clin Invest. 2006. PMID: 16470243 Free PMC article.
-
Effects of PACAP Deficiency on Immune Dysfunction and Peyer's Patch Integrity in Adult Mice.Int J Mol Sci. 2024 Oct 3;25(19):10676. doi: 10.3390/ijms251910676. Int J Mol Sci. 2024. PMID: 39409005 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources