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Guideline
. 2001 Jul;50(1):121-7.
doi: 10.1002/ana.1032.

Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis

W I McDonald  1 , A Compston, G Edan, D Goodkin, H P Hartung, F D Lublin, H F McFarland, D W Paty, C H Polman, S C Reingold, M Sandberg-Wollheim, W Sibley, A Thompson, S van den Noort, B Y Weinshenker, J S Wolinsky
Affiliations
Guideline

Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis

W I McDonald et al. Ann Neurol. 2001 Jul.

Abstract

The International Panel on MS Diagnosis presents revised diagnostic criteria for multiple sclerosis (MS). The focus remains on the objective demonstration of dissemination of lesions in both time and space. Magnetic resonance imaging is integrated with dinical and other paraclinical diagnostic methods. The revised criteria facilitate the diagnosis of MS in patients with a variety of presentations, including "monosymptomatic" disease suggestive of MS, disease with a typical relapsing-remitting course, and disease with insidious progression, without clear attacks and remissions. Previously used terms such as "clinically definite" and "probable MS" are no longer recommended. The outcome of a diagnostic evaluation is either MS, "possible MS" (for those at risk for MS, but for whom diagnostic evaluation is equivocal), or "not MS."

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  • Reply: To PMID 11456302.
    Polman CH, Reingold SC, Weinshenker BG. Polman CH, et al. Ann Neurol. 2006 May;59(5):871. doi: 10.1002/ana.20849. Ann Neurol. 2006. PMID: 16634009 No abstract available.

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