Review
doi: 10.1038/35080103.
XIAP, the guardian angel
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- PMID: 11433370
- DOI: 10.1038/35080103
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Review
XIAP, the guardian angel
Nat Rev Mol Cell Biol.
2001 Jul.
Abstract
Controlling the activity of caspases is essential for the appropriate execution of cell death and the regulation of cell survival. One cellular inhibitor of apoptosis, XIAP, has emerged as a crucial regulator of caspases, and is itself subject to complex negative regulation.
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