Field studies on the sensitivity and specificity of an immunochromatographic test for the detection of Plasmodium falciparum malaria in tribal areas of Orissa
- PMID: 11398664
Field studies on the sensitivity and specificity of an immunochromatographic test for the detection of Plasmodium falciparum malaria in tribal areas of Orissa
Abstract
A rapid immunodiagnostic test developed by an Australian Biotechnology company for the diagnosis of Plasmodium falciparum in the peripheral blood has been evaluated in the field for its sensitivity, specificity and efficacy in comparison to microscopic examination. The results showed that the tests sensitivity, specificity and efficacy were 98.2, 96.9 and 97.5 per cent respectively. The positive and negative predictive values of the test were 96.4 and 98.4 per cent respectively. The test when compared to the conventional microscopy did not show any statistically significant difference suggesting that the two diagnostic methods are equally good. The test performed did not show cross-reactions with other parasite species. It is a simple and rapid field diagnostic method, which does not require any expensive laboratory equipment or skilled personnel.
Similar articles
-
Comparison of the OptiMAL rapid test with routine microscopic examination of Giemsa-Stained Thick Blood Film for diagnosis of malaria.J Med Assoc Thai. 2001 Mar;84(3):357-63. J Med Assoc Thai. 2001. PMID: 11460936
-
Rapid diagnosis of falciparum malaria by detection of Plasmodium falciparum HRP-2 antigen.J Assoc Physicians India. 1999 Nov;47(11):1076-8. J Assoc Physicians India. 1999. PMID: 10862317
-
[Serum HRP-2 antigens and imported Plasmodium falciparum malaria: comparison of ParaSight-F and ICT malaria P.f].Med Trop (Mars). 1997;57(4):353-6. Med Trop (Mars). 1997. PMID: 9612775 French.
-
Clinical trials of a new immunochromatographic test for diagnosis of Plasmodium falciparum malaria in Goa.Indian J Malariol. 1996 Dec;33(4):166-72. Indian J Malariol. 1996. PMID: 9125830 Clinical Trial.
-
Laboratory diagnosis of malaria: conventional and rapid diagnostic methods.Arch Pathol Lab Med. 2013 Jun;137(6):805-11. doi: 10.5858/arpa.2011-0602-RA. Arch Pathol Lab Med. 2013. PMID: 23721276 Review.
Cited by
-
Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries.Cochrane Database Syst Rev. 2011 Jul 6;2011(7):CD008122. doi: 10.1002/14651858.CD008122.pub2. Cochrane Database Syst Rev. 2011. PMID: 21735422 Free PMC article. Review.
-
Rapid diagnostic tests for diagnosing uncomplicated non-falciparum or Plasmodium vivax malaria in endemic countries.Cochrane Database Syst Rev. 2014 Dec 18;2014(12):CD011431. doi: 10.1002/14651858.CD011431. Cochrane Database Syst Rev. 2014. PMID: 25519857 Free PMC article. Review.